The melody of Sex On Fire by Kings Of Leon runs 171 notes across 53 bars, 2:50 long in E at 150 beats per minute. The tab sits almost entirely in the first two frets, one note at a time — no chords to barre and no strumming pattern to keep up with. A piano backing track plays the chords and bass underneath, so the line you are learning sounds like the record even at half speed.
Prefer to strum and sing it instead? Sex On Fire chords and lyrics.