The melody of I Can’t Turn You Loose by Otis Redding runs 177 notes across 19 bars, 2:02 long in C at 126 beats per minute. The tab sits almost entirely in the first two frets, one note at a time — no chords to barre and no strumming pattern to keep up with. A piano backing track plays the chords and bass underneath, so the line you are learning sounds like the record even at half speed.
Prefer to strum and sing it instead? I Can’t Turn You Loose chords and lyrics.