The melody of 3x5 by John Mayer runs 221 notes across 79 bars, 4:46 long in Fm at 140 beats per minute. The tab sits almost entirely in the first two frets, one note at a time — no chords to barre and no strumming pattern to keep up with. A piano backing track plays the chords and bass underneath, so the line you are learning sounds like the record even at half speed.
Prefer to strum and sing it instead? 3x5 chords and lyrics.